Conventional heart failure drugs lead to increased excretion of vitamin B1 (thiamine), thereby inducing thiamine deficiency and further compromising heart function. Scientists at the university hospital of Bern, Switzerland, evaluated the effect of high-dose thiamine supplementation in heart failure patients. Patients with impaired heart pumping who took conventional drugs for chronic heart failure received 300 mg/day of thiamine or a placebo for 28 days. After a therapy break of 6 weeks, patients reversed medication for another 28 days. Heart pumping function significantly increased compared with the results after taking the placebo. In conclusion, thiamine supplementation showed beneficial effects on the heart function of patients using conventional heart failure drugs. For more details, see the study.
Schoenenberger et al.