This study analyzed the effect of maternal prenatal vitamin supplementation with folic acid and other vitamins on childhood leukemia. Data on prenatal use of folic acid and vitamins were obtained from 12 studies, including more than 7,000 children with leukemia and 11,635 without leukemia. The results suggested that maternal prenatal use of vitamins and folic acid reduces the risk of leukemia in offspring. More details can be found in the study.
Catherine Metayer, Elizabeth Milne, John D Dockerty, Jacqueline Clavel, Maria S Pombo-de-Oliveira, Catharina Wesseling, Logan G Spector, Joachim Schüz, Eleni Petridou, Sameera Ezzat, Bruce K Armstrong, Jérémie Rudant, Sergio Koifman, Peter Kaatsch, Maria Moschovi, Wafaa M Rashed, Steve Selvin, Kathryn McCauley, Rayjean J Hung, Alice Y Kang, Claire Infante-Rivard