This French study investigated whether a micronutrient combination containing, among others, coenzyme Q10 and magnesium is effective in preventing migraine. Adult patients suffering from migraine were administered one tablet of this combination per day for 3 months during the study. Supplementation significantly reduced the number of days with migraine headaches. This decrease was progressive throughout supplementation. After three months, 75% of the patients experienced a reduction of at least 50% in the number of days with migraine headaches. The proportion of patients with anxiety and depressive symptoms decreased between the start and the third month of supplementation from 61.9% to 35% (for depression) and 52.4% to 30% (for anxiety), respectively. Additionally, an improvement in quality of life was observed. In conclusion, this micronutrient combination was shown to be beneficial and safe for preventing migraine in adult patients. Further details can be found in the study.
Guilbot et al.