Summary In another randomized and controlled clinical trial, a joint team of researchers from the University Hospitals of Frankfurt and Hanover examined the effects of vitamin D administration on diabetes progression. The results of this clinical study showed that vitamin D supplementation significantly reduced insulin demands and significantly improved long-term blood glucose levels (HbA1c). No…
Summary A randomized clinical trial investigated the effect of vitamin C supplementation on blood glucose control and blood pressure in diabetic patients. After 4 months of vitamin C supplementation, participants showed an improvement in blood sugar levels and a reduction in blood pressure compared to the placebo group. Further details can be found in the…
Summary A randomized, controlled clinical trial at Cairo University Medical Clinic examined the effect of a dietary supplement containing a combination of B vitamins (B1, B6 and B12) on patients with type 1 diabetes. After only 3 months, this dietary supplement led to a significant decrease in fasting blood glucose levels, long-term blood glucose (HbA1c),…
Summary Diabetes is a known risk factor during pregnancy, when the disease can lead to serious complications as a result of metabolic disorder. A randomized, controlled study at Shanghai University Hospital investigated the effect of vitamin D on the progression of gestational diabetes. Supplementation with high-dose vitamin D significantly improved the insulin needs and other…
Summary 60 patients with type 2 diabetes and low vitamin D levels were enrolled in a placebo-controlled, randomized clinical trial to investigate the effect of vitamin D supplementation on the progression of the disease. Patients who received a vitamin D supplement had a significant reduction in their long-term diabetes score (HbA1c). Blood pressure and blood…
Summary This study evaluated the effect of vitamins supplementation in diabetic people. The study on consumption of vitamins C, E and combination of C and E was completed in 170 patients with type 2 diabetes on consumption of vitamins C, E and combination of C and E. Blood pressure, blood sugar levels and oxidative stress…
Summary This study examined the effect of vitamin C administration on oxidative stress (imbalance between the production of free radicals production and the body´s antioxidant defences) in pregnant women with diabetes (gestational diabetes). 200 women with gestational diabetes were given vitamin C or no supplementation. The results showed that vitamin C reverses the oxidative stresses…
Summary This study assessed the effect of vitamin D supplementation on the risk of diabetes. 130 men without diabetes and with vitamin D deficiency/insufficiency were given vitamin D or no supplementation. The results showed that the men administered with vitamin D had maintained insulin levels (the action of insulin is important in decreasing blood sugars)…
Summary This review provides an overview of the currently available evidences on the effect of vitamin K supplementation in the management of diabetes. The results reported the beneficial role of vitamin K supplementation in preventing insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood sugars) and…
Summary This publication presents data on blood levels of vitamin D in patients with diabetes and in people without the disease. The results indicated that both type 1 and type 2 diabetic patients have lower levels of vitamin D when compared with non-diabetic people. More details can be found in the study. References Role of…
Summary This study assessed the effect of vitamin D in patients with painful diabetic neuropathy (nerve damage). Vitamin D was administered to 143 patients with diabetes and neuropathy. The results showed that treatment with vitamin D is associated with a significant decrease in the symptoms of painful diabetic neuropathy. More details can be found in…
Summary This study determined the effect of vitamin C infusions on the function of the endothelium (inner lining of blood vessels) in diabetic patients. 8 adolescents with diabetes were included in the study. The results showed that vitamin C was effective against the endothelial dysfunction in adolescents with diabetes. More details can be found in…
Summary This study investigated the blood levels of vitamin D in diabetic patients. 100 adolescents, including 60 with diabetes and 40 without the disease, were included. The results showed that vitamin D deficiency was associated with poor control of blood sugar levels in adolescents with diabetes. The authors concluded that vitamin D deficiency should be…
Summary Diabetic patients can suffer from insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood sugars) and oxidative stress (imbalance between the production of free radicals production and the body´s antioxidant defenses). This study investigated the effects of vitamin C supplementation on insulin resistance and oxidative…
Summary The aim of this study was to examine whether vitamin C is capable of reducing inflammation in obese adults with high blood pressure and/or diabetes. 64 patients were given either 500 mg vitamin C twice a day or no treatment. The results showed that vitamin C reduced inflammation in obese patients with high blood…
Summary This research collected studies on the use of dietary supplements in the management of high blood pressure and diabetes. The studies showed that micronutrients were effective and safe substitutes for toxic and expensive conventional drugs. Moreover, it turned out that micronutrients are generally free from side effects. The authors therefore concluded that dietary supplements…
Summary This study examined the beneficial effects of resveratrol on diabetes-induced kidney disease (diabetic nephropathy). Diabetic rats were treated with or without resveratrol at 0.75mg/kg body weight 3 times a day for 8 weeks. The results revealed that resveratrol ameliorates changes associated with early diabetic nephropathy. Further details can be found in the study. References…
Summary The present study examined the beneficial effects of the natural compound resveratrol on diabetic changes of blood vessel walls (diabetic vasculopathy). The study was conducted with rats suffering from (artificially induced) diabetes. In the study, the animals were treated with or without resveratrol (at 0.75 mg/kg body weight) three times a day for 4-8…
Summary This study was conducted to evaluate the effect of resveratrol in type 2 diabetic patients. Resveratrol is a plant polyphenol that has been found to have beneficial effects on cardiovascular health. 19 diabetes patients were randomly assigned into two groups: a resveratrol group receiving 5 mg resveratrol twice daily and a control group receiving…
Summary The present study explored the protective effects of resveratrol in diabetes-induced kidney disease (diabetic nephropathy) by assessing markers of oxidative stress. Oxidative stress is an imbalance between free radicals production and the body’s antioxidant defenses. The analysis demonstrated the protective nature of resveratrol by attenuating markers of oxidative stress in renal tissues of diabetic…
Summary This study aimed to investigate the protective effects of resveratrol in early-stage diabetes-induced kidney disease (diabetic nephropathy, DN). The experiment was performed in diabetic rats. The results suggested that resveratrol protects against oxidative stress, i.e. an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects…
Summary This study investigated the protective effect of the natural compound resveratrol on diabetic nephropathy, a kidney disease that occurs in people with type 1 or type 2 diabetes. Oxidative stress plays a crucial role in the development of this complication. In order to examine the effect of resveratrol on kidney function and oxidative stress,…
Summary The aim of this study was to identify vitamin D deficiency among 157 patients with prediabetes (high blood sugar levels but not in the diabetes range) and to evaluate the relationship between vitamin D status and insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood…
Summary This study investigated the relationship between vitamin D and the incidence of type 2 diabetes. 961 patients were followed over a period of 11 years. The results showed a significantly reduced risk for diabetes in people with higher vitamin D levels. Further details can be found in the study. References Deep Dutta, Indira Maisnam, Ankit Shrivastava, Anirban…
Summary The aim of this review was to examine the association between vitamin D status and the incidence of type 2 diabetes. A total of 19 studies was included. This analysis showed that individuals with the highest vitamin D status (>25 ng/ml) had a 43% lower risk of developing diabetes. Further details can be found in…
Summary This study examined the relationships between vitamin D and diabetes risk factors (i.e. blood sugar levels) in obese children. Data of 411 obese American children were recorded. The results showed that lower vitamin D levels were associated with increased risk factors for diabetes in obese children. Further details can be found in the study.…
Summary The objective of this study was to determine whether vitamin D deficiency was associated with type 2 diabetes among HIV-infected patients. Data were obtained from all participants enrolled in the prospective Modena (Italy) HIV Metabolic Clinic Cohort. Results showed that HIV-infected patients with diabetes had lower vitamin D levels compared with those without diabetes.…
Summary This study evaluated oxidative stress (imbalance between free radicals production and the body’s antioxidant defenses) in diabetic patients by estimating the effect of vitamin E. A total of 40 children (20 diabetic patients plus 20 healthy controls) were examined in the study. The results demonstrated that vitamin E ameliorates oxidative stress in diabetic patients…
Summary This study analyzed the link between a diet high in low-fat dairy products and diabetes risk in women after menopause (postmenopause). 82,076 postmenopausal women who did not report diabetes at enrollment were involved in the study. The intakes of dairy products were evaluated by means of a questionnaire at the start of the study…
Summary This study was performed to test the effects of two Mediterranean diets on the incidence of diabetes. 418 non-diabetic adults aged 55-80 years were randomly assigned to a control group or to one of two Mediterranean Diets, supplemented with either free virgin olive oil or nuts. The researchers found that Mediterranean Diets were effective…
Summary This study investigated the effects of resveratrol in regulating hyperglycemia (high blood sugar levels), pro-inflammatory factors, insulin secretion and antioxidant defenses in diabetes. Oral resveratrol was administered (5 mg/kg body weight) to diabetic rats for 30 days. The results of the present investigation demonstrated that resveratrol exhibited significant anti-diabetic effects by attenuating hyperglycemia, enhancing…
Summary The present study was designed to examine the effect of curcumin on kidney (renal) function and oxidative stress (imbalance between free radicals and the body antioxidant defenses) in diabetes. Diabetic rats were divided into four groups, namely control rats, diabetic rats and diabetic rats treated with curcumin (15 and 30 mg/kg) for 2 weeks.…
Summary This study was conducted to evaluate the benefit of high-dose vitamin D supplementation in diabetic patients with cardiovascular complications. 47 patients with type 2 diabetes were assigned into two groups: Group 1 received a vitamin D supplement at a dose of 1000 U (units) per day for 12 months. Group 2 received matching placebo…
Summary This study analyzed the protective effect of turmeric and curcumin (the plant turmeric is a source of curcumin) on oxidative stress, i.e. an imbalance between free radicals production and the body’s antioxidant defenses. Oxidative stress is associated with diabetes complications. Diabetic rats were fed either only their normal diet or a diet containing curcumin…
Summary This study determined whether vitamin D supplementation improved the function of the pancreas in adults at high risk of diabetes. The pancreasis important for the insulin production and the regulation of blood sugar levels. 92 adults received either vitamin D or calcium for 16 weeks. The researchers found that participants receiving vitamin D supplements…
Summary This study examined associations between the intake of omega-3 fatty acids from fish and shellfish and the risk of diabetes. Data from 51,963 men and 64,193 women free of diabetes, cardiovascular disease and cancer were analyzed. The results highlighted a reduced diabetes risk in women with a high fish and shellfish intake. Further details…
Summary The objective of this study was to examine the association between vitamin D levels in the blood and diabetes mellitus. Analyses were carried out on 5787 Korean adults (2453 men and 3334 women) who were 20 years or older. The results showed that low vitamin D blood levels were associated with a high risk…
Summary This study tested the associations between vitamin D levels and the risk of developing diabetes and insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood sugars) during pregnancy. Blood samples were taken from 655 participants in the first (6-13 weeks) and second (24-28 weeks) trimester.…
Summary This study aimed to determine and compare the vitamin D status of adults in Saudi Arabia with and without type 1 diabetes mellitus. A total of 60 adults with type 1 diabetes and 60 healthy controls were included in the study. The results revealed that vitamin D deficiencies were frequently found among type 1…
Summary The objective of this study was to identify whether omega-3 fatty acids protect against type 2 diabetes. To this end, the researchers examined the association between the risk of type 2 diabetes and the consumption of different types of polyunsaturated fatty acids in 43,176 Chinese men and women free of chronic disease. Fatty acids…
Summary C-reactive protein is a marker for inflammation and higher concentrations are associated with an increased risk for diabetes. This study determined whether magnesium supplementation modifies C-reactive protein (hsCRP) levels in healthy adults with prediabetes (high blood sugar levels but not in the diabetes range) and low magnesium levels (hypomagnesemia). A total of 62 men…
Summary This study analyzed the relation between vitamin D and anemia (low levels of red blood cells/hemoglobin in the blood) in patients with type 2 diabetes. After hemoglobin and vitamin D concentrations were evaluated in male patients with type 2 diabetes, it was found that vitamin D is associated with higher hemoglobin levels and a…
Summary The present study examined the relation between omega-3 fatty acids and diabetes in 3088 men and women with an average age of 75 years. The results showed that individuals with the highest blood concentrations of omega-3 fatty acids had a lower risk of diabetes. Further details can be found in the study. References Shu…
Summary This study examined whether vitamin C levels, fruit and vegetable intake are associated with the risk of type 2 diabetes. Participants were men and women aged 40 to 75 years. Food intake was evaluated by means of a questionnaire. Vitamin C levels and the habitual intake of fruit and vegetables were then assessed. It…
Summary Oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses) is one of the major mechanisms involved in the development of diabetic nephropathy. This study examined the link between quercetin (antioxidant), diabetes and diabetic nephropathy (renal dysfunction). Quercetin (10 mg/kg per day) was given for 4 weeks in both control and diabetic…