Summary Researchers from Iran conducted this study to determine the effects of folate supplementation on glucose (sugar) regulation in overweight and obese men with type 2 diabetes who also used conventional drugs. 48 participants were divided into two groups receiving either folic acid (5 mg/day) or a placebo for 8 weeks. Supplementation with folic acid…
Summary Taiwanese researchers explored the status of chromium, zinc, and magnesium in patients with type 1 diabetes. All these micronutrients are involved in glucose metabolism, among others. The findings showed that the concentrations of these trace elements (especially magnesium and zinc) were lower in the blood of type 1 diabetes patients than in study participants…
Summary This study, conducted by scientists from a research institute in Auckland, New Zealand, aimed to investigate the effect of improved vitamin D levels on characteristics of diabetes, like insulin resistance. The patients were administered 100 µg (4000 IU) of vitamin D3 (42 women) or a placebo (39 women) daily for 6 months. Supplementation with…
Summary This Indian study aimed to examine the effect of oral vitamin C, in combination with an often used conventional drug, on fasting and postmeal blood glucose (sugar) levels as well as long-term blood glucose levels (HbA1c) and vitamin C levels in type 2 diabetes. 70 patients with type 2 diabetes participated in this 12-week…
Summary The objective of this trial was to determine whether oral magnesium supplementation improves the function of insulin-producing cells (beta cells in the pancreas) in non-diabetic individuals with magnesium deficiency. Non-diabetic participants with normal blood pressure and low magnesium levels received either magnesium (54 participants) or a placebo (52 participants) daily for 3 months. Beta…
Summary Vitamin B1 (thiamine) deficiency is prevalent in patients with type 2 diabetes, suggesting that correcting this deficiency may provide beneficial cardiovascular and metabolic effects. The objective of this study was to determine whether vitamin B1 supplementation is associated with an improvement of related parameters, like blood pressure and fasting blood glucose levels in patients…
Summary This study, conducted by Indian research departments, aimed to investigate the differences in dietary intake of macro- and micronutrients in elderly patients with type 2 diabetes mellitus, with and without food ulcers. Elderly type 2 diabetes patients with foot ulcers (79 patients) and type 2 diabetes patients without foot ulcers (59 patients) were studied.…
Summary This study, executed by medical schools in Boston, USA, explored whether magnesium intake is associated with a lower risk of diabetes type 2, especially in the context of a diet low in cereal fiber and high in low-quality carbohydrates, which provide quick energy but are mainly devoid of nutrients. Dietary magnesium intake was assessed…
Summary Vitamins and trace elements are essential for a well-functioning body, and micronutrient deficiencies can lead to widespread health problems. This review, conducted by American research departments, discusses the consequences of micronutrient deficiencies in diabetes and insulin resistance. The level of micronutrients in the human body depends on many factors, like the origin and composition…
Summary This study, executed by a research department in Tehran, Iran, aimed to determine if micronutrients can improve neuropathy indicators in type 2 diabetes. 75 patients with type 2 diabetes were assigned to one of the following three treatment groups: The first group received a combination of zinc (20 mg), magnesium (250 mg), vitamin C…
Summary Research shows that oxidative stress and inflammation are important factors in diabetes. This study, executed by universities from Iran and Canada, aimed to determine whether supplements containing magnesium, zinc, calcium, and vitamin D can improve inflammation and oxidative stress in women with gestational diabetes. 60 patients with gestational diabetes were assigned to take the…
Summary Vitamin D deficiency is associated with a greater risk of developing type 2 diabetes mellitus. This study, executed by a research department in London, UK, determined the effect of a vitamin D and calcium replacement therapy on regulating glucose levels in Asian patients with type 2 diabetes mellitus and low vitamin D levels. The…
Summary Magnesium is a micronutrient with several benefits, including anti-inflammatory properties. This study, executed by Iranian and Canadian universities, aimed to evaluate the effects of magnesium supplementation on inflammatory processes and pregnancy outcomes in women diagnosed with gestational diabetes. The trial was conducted with 36 women, 18 to 40 years old, who were allocated to…
Summary High glucose levels result in an overproduction of free radicals, inducing oxidative stress and impairing the function of antioxidants. This trial, conducted by a research institute in India, evaluated the effect of 3 months of antioxidant supplementation in Indian children with type 1 diabetes. 90 children were allocated to three groups: 31 healthy children…
Summary This study, conducted by the Austrian universities of Graz, Vienna, and Salzburg, investigated the suppressive effect of specific regulatory immune cells in young patients with new-onset type 1 diabetes. 30 young patients were assigned to receive vitamin D3 (70 IU/kg body weight/day) or a placebo for 12 months. The immune cells (Tregs), which are…
Summary Vitamin D deficiency is prevalent in adolescents with type 1 diabetes and is associated with diabetes-related vascular complaints in adulthood. This trial, conducted by research departments from Canada and Israel, aimed to assess the efficacy of vitamin D treatment on the function of blood vessels and indicators of kidney-related inflammation in this patient group.…
Summary This review summarized current knowledge on the effect of vitamin D on type 1 and type 2 diabetes mellitus and on vascular complications associated with this disease. Several studies have provided evidence for the role of vitamin D in diabetes mellitus and found a potential link between low vitamin D levels and diabetes. More…
Summary Magnesium and vitamin E exert multiple beneficial effects on glucose (sugar) and lipid (fat) metabolism. This study, executed by Iranian researchers, aimed to determine the effects of magnesium and vitamin E on the metabolism of women with gestational diabetes. This study was conducted with 60 subjects diagnosed with gestational diabetes, aged 18 to 40…
Summary This trial, executed by three Indian research departments, aimed to assess the effects of vitamin D and calcium on metabolic factors and oxidative stress levels in women with gestational diabetes. The trial was conducted on 70 women diagnosed with gestational diabetes who received either 1000 IU (25 µg) of vitamin D and 1000 mg…
Summary Researchers from Iran studied the effects of a supplement containing different micronutrients (magnesium, zinc, calcium, and vitamin D) on blood glucose (sugar) levels and cardiometabolic risk factors in patients with gestational diabetes mellitus. 60 patients, aged 18 to 40 years, were divided into two groups of each 30 participants who received either the supplement…
Summary This study assessed the effects of a combined vitamin D and probiotic supplementation on gestational diabetes. 87 women with gestational diabetes participated in the study. They were randomly assigned to three groups receiving either vitamin D plus probiotics (30 women), only probiotics (29 women), or a placebo (28 women) for 6 weeks. Vitamin D…
Summary This study aimed to determine the effects of omega-3 fatty acids and vitamin E on blood glucose (sugar) parameters and lipid concentrations in women with gestational diabetes who did not use oral diabetes medication. The study was carried out with 60 patients. The participants were randomly allocated to a group taking omega-3 fatty acids…
Summary This Indian study aimed to assess the efficacy, tolerability, and safety of vitamin K in patients with peripheral neuropathy (conditions that involve damage to nerves outside of the central nervous system). The study was conducted on 100 patients with peripheral neuropathy who suffered from vitamin B12 deficiency or type 2 diabetes mellitus. The patients…
Summary Alpha-lipoic acid is an antioxidant that is made naturally in the body. It serves vital functions at the cellular level, such as energy production. The aim of this study was to explore the effect of alpha-lipoic acid on gestational diabetes. To this end, 60 women with gestational diabetes were divided into a supplementation group…
Summary Several studies have shown that magnesium intake decreases the risk of type 2 diabetes. In this Japanese study, the association between magnesium intake and the incidence of type 2 diabetes was examined. Almost 2000 subjects without diabetes, aged between 40 and 79 years, underwent a glucose test and were followed up for 15.6 years.…
Summary Gestational diabetes and vitamin D deficiency are related to insulin resistance and an impaired function of beta cells in the pancreas which produces insulin. This study, conducted by researchers from Denmark, Malaysia, and Italy, aimed to evaluate the impact of vitamin D on the glucose metabolism of Asian women with gestational diabetes during 24-28…
Summary Diets and lifestyles in developed countries promote deficiencies of micronutrients, particularly vitamin C and D, and are associated with diabetes, for instance. This Australian review evaluated results from studies examining the potential of vitamin C and D in reversing defects in glucose regulation and preventing type 2 diabetes. Several studies suggest an association between…
Summary This Iranian trial was executed to investigate the effects of alpha-lipoic acid supplementation on oxidative stress in women with gestational diabetes. 60 women with gestational diabetes at 24 to 28 weeks of pregnancy were selected and divided into a supplementation group (30 women), receiving 300 mg/day of alpha-lipoic acid for 8 weeks, and a…
Summary This study, conducted by medical universities in Rome, Italy, and London, UK, aimed to evaluate whether inositol, a vitamin-like substance, plus folic acid, may improve glucose levels and reduce insulin resistance in overweight or obese type 1 diabetes patients. Insulin resistance is when cells in muscles, fat, and liver don’t respond well to insulin…
Summary Gestational diabetes is diabetes diagnosed for the first time during pregnancy (gestation). This Iranian study aimed to determine the effect of zinc supplementation on glucose (sugar) levels and lipid (fat) concentrations in women with gestational diabetes. The study was performed with 58 women (aged 18 to 40 years) diagnosed with gestational diabetes. Patients were…
Summary This Iranian study aimed to assess the effects of selenium supplementation on the metabolism of pregnant women with gestational diabetes. The study was performed on 70 women with gestational diabetes who were not treated with conventional medication. The patients were randomly assigned to receive either 200 µg of selenium (35 patients) or a placebo…
Summary Vitamins and trace elements are essential for a well-functioning human body, and micronutrient deficiencies can lead to widespread health problems. This review, conducted by American research departments, discusses the consequences of micronutrient deficiencies in diabetes and insulin resistance. The level of micronutrients in the human body depends on many factors, like the origin and…
Summary This trial, executed by Iranian researchers, aimed to determine the effects of zinc and vitamin E on the metabolism and factors influencing insulin and lipid metabolism in women with gestational diabetes. 54 women aged 18 to 40 years and diagnosed with gestational diabetes participated in this study. The patients were allocated to two intervention…
Summary This study aimed to determine the effects of a combined intake of probiotics and selenium on glucose and lipid levels in patients with gestational diabetes. To this end, 60 patients were allocated to two groups receiving either a placebo (30 participants) or a supplement containing probiotic plus selenium (30 participants) daily for 6 weeks.…
Summary High blood sugar (glucose) levels are associated with diabetes and prediabetes. Prediabetes is when blood sugar is high, but not high enough to be classified as diabetes. This study, conducted by two Indian research departments, evaluated the effect of 12 months of vitamin D supplementation on glucose levels and the progression of prediabetes to…
Summary High blood glucose (sugar) levels are a common problem for people with diabetes. This Iranian study aimed to evaluate changes in glucose levels following vitamin D3 supplementation in children with type 1 diabetes mellitus and vitamin D deficiency. Before the study, after three months, and at the end of the study, vitamin D levels…
Summary High blood glucose levels are associated with the development of diabetes, which is a common disease in Western societies. Researchers from Sweden and Germany examined whether a specific nutritional supplement containing various amino acids improves blood glucose levels in non-diabetic adults. To this end, 60 overweight healthy participants were administered with the mentioned supplement…
Summary An Iranian study aimed to evaluate the effects of selenium supplementation on the function of the metabolism, including glucose balance, inflammation levels, and oxidative stress in patients with diabetes type 2 and coronary heart disease. 60 patients were divided into two groups. For 8 weeks, the first group (30 patients) received 200 µg of…
Summary Obesity is associated with chronic inflammation. Thus, this study investigated the anti-inflammatory capacity of vitamin C in obese patients. 64 obese participants with high blood pressure and/or diabetes and high levels of inflammatory markers were enrolled into either the experimental group (31 patients) or the control group (33 patients). The experimental group was treated…
Summary This study, executed by an Iranian and a Croatian university, aimed to analyze the effects of magnesium and zinc supplements on glucose levels, oxidative stress, and inflammation in patients with coronary artery disease and type 2 diabetes. In this study, 60 patients were divided into either a group receiving a placebo or a group…
Summary Researchers from Sri Lanka and Australia examined the effects of a specific micronutrient product containing lysine, zinc, and vitamin C, on pre-diabetes. 110 participants were recruited and divided into two groups: an intervention group (participants receiving the micronutrient product) and a placebo group. The results showed that the micronutrient supplement improved important parameters involved…
Summary Studies suggest that vitamin D deficiency is associated with metabolic disorders such as hyperglycemia (high blood sugar) and dyslipidemia (abnormal amount of lipids in the blood), as well as increased oxidative stress, which can cause a variety of diseases. Scientists at the Medical University of Łódź (Poland) explored the effect of vitamin D supplementation…
Summary This study by various U.S. research institutes aimed to find out whether vitamin D supplementation affects the risk of diabetes. The study included 2,158 participants with prediabetes (elevated blood sugar levels that fall below the threshold to diagnose diabetes) who were assigned to either a vitamin D group (1,074 individuals) or a placebo group…
Summary Researchers at the University of Pittsburgh (USA) studied the effect of vitamin D supplementation in 225 obese children with vitamin D deficiency. The study participants received either 600 IU or 1000 IU or 2000 IU of vitamin D3 daily for 6 months. An improvement in blood pressure, fasting glucose concentration and insulin sensitivity was…
Summary A randomized clinical trial investigated the effect of vitamin C supplementation on blood glucose control and blood pressure in diabetic patients. After 4 months of vitamin C supplementation, participants showed an improvement in blood sugar levels and a reduction in blood pressure compared to the placebo group. Further details can be found in the…
Summary Diabetes is a known risk factor during pregnancy, when the disease can lead to serious complications as a result of metabolic disorder. A randomized, controlled study at Shanghai University Hospital investigated the effect of vitamin D on the progression of gestational diabetes. Supplementation with high-dose vitamin D significantly improved the insulin needs and other…
Summary In another randomized and controlled clinical trial, a joint team of researchers from the University Hospitals of Frankfurt and Hanover examined the effects of vitamin D administration on diabetes progression. The results of this clinical study showed that vitamin D supplementation significantly reduced insulin demands and significantly improved long-term blood glucose levels (HbA1c). No…
Summary A randomized, controlled clinical trial at Cairo University Medical Clinic examined the effect of a dietary supplement containing a combination of B vitamins (B1, B6 and B12) on patients with type 1 diabetes. After only 3 months, this dietary supplement led to a significant decrease in fasting blood glucose levels, long-term blood glucose (HbA1c),…
Summary 60 patients with type 2 diabetes and low vitamin D levels were enrolled in a placebo-controlled, randomized clinical trial to investigate the effect of vitamin D supplementation on the progression of the disease. Patients who received a vitamin D supplement had a significant reduction in their long-term diabetes score (HbA1c). Blood pressure and blood…
Summary This study evaluated the effect of vitamins supplementation in diabetic people. The study on consumption of vitamins C, E and combination of C and E was completed in 170 patients with type 2 diabetes on consumption of vitamins C, E and combination of C and E. Blood pressure, blood sugar levels and oxidative stress…